MPZ

To clone novel myelin protein related genes, two human ESTs, which shared significant similarity with the human myelin protein zero gene, were found by the comparison of homologue between the cDNA coding region sequences of MPZ gene and the EST database of NCBI.

为克隆新的髓鞘蛋白相关基因，将MPZ基因编码区cDNA序列与EST数据库进行同源性比较，得到与MPZ显著相似的2个EST，构建成801bp的重叠群。

Methods The effects of MPZ on the proliferation of K562 leukemia cells were in vitro studied in terms of morphology observation, cell number numeration both in liquid and in semi solid colony cultures and UV absorption in the MTT assay.

方法：采用形态观察、液体培养、集落培养及MTT实验检测MPZ对K562细胞增殖的影响，并观察其形态学变化。

Objective To evaluate the inhibitory effects of a novel 2 aminosteroid ( MPZ) on the proliferation of K562 leukemia cells.

目的：观察2氨基甾体（MPZ）对慢粒白血病细胞系K562细胞增殖的作用。

Results 21.9 % of the CMT pedigrees had mutations in the Cx 32, MPZ and PMP 22 genes.

结果　21.9%的CMT家系患者有Cx32 、 MPZ和 PMP22基因的突变.

Torco oil also contains MPZ additive package that reduce engine wear.

Torco石油还包含MPZ添加剂封装,减轻发动机磨损.