ODN

CpG-ODN , finding in bacteria, the oligodeoxynecleotides containing non-methylated CpG dinucleotides, has immune activation.

CpG -ODN 是一些发现于细菌中含有未甲基化的CpG二核苷酸对并且具有免疫激活作用的寡核苷酸.

CpG ODN also induce maturation of dendritic cells and facilitate activation of Thl immune response.

CpG基序是存在于细菌DNA中 具有强烈免疫刺激活性的特定序列.

CpG-N ODN could inhibit the surface binding and internalization of CpG-S ODN.

CpG-NODN对 CpG -S ODN在 hPBMC细胞表面的结合和内化具有抑制作用.

METHODS Chitosan-CpG ODN nanoparticles were prepared by complex coacervation method.

方法:采用复凝聚方法制备CpGODN壳聚糖纳米粒.

Conclusion CpG ODN may stimulate PBMC activity, and improve the dilling activity of PBMC on HO 8910.

结论CpGODN可刺激PBMC增殖, 提高PBMC的杀伤活性,从而增强机体的特异性和非特异性免疫效应.

Objective To study the immunotherapy role of CpG ODN ( CpG oligodeoxynucleotide ) on tumor.

目的探讨合成含CpG基 序的寡核苷酸 ( CpGODN ) 在肿瘤免疫治疗中的研究.

Conclusion CS CpG-ODN gene carriers were shown to effectively improve the immunoenhancing effect of CpG-ODN .

结论CSCpG -ODN 基因载体能有效提高CpG -ODN 免疫促进作用.