TNZ

RESULTS: The effective rate of TNZ delivery device in adult periodontitis patients was 93.33%, which was significantly higher than that of the control group ( 73.33%).

结果：替硝唑棒治疗成人牙周炎的疗效显效率为93.33%，优于对照组73.33%。

Comparatively the product TNZ is in inferior position both in production capacity, manufacturing cost as well as in market expanding, product market is shrinking continuously.

替硝唑产品在生产能力、生产成本、市场拓展能力等方面处于相对劣势，产品市场不断痿缩。

Objective To test the effect of TNZ on oral spirochete among 24 patients with severe periodontitis.

目的检测24例重度牙周炎患者口腔螺旋体对替硝唑的敏感性。

OBJECTIVE To prepare the tinidazole β-cyclodextrin inclusion compound, to improve the stability and solubility of tinidazole ( TNZ).

目的研究替硝唑-β-环糊精包合物的制备工艺。

The first part was divided into 5 teams, each team was breathed TNZ solution of 100mg/ kg weight into stomach in 5 days continuously.

第一批60只KM小鼠分为5组，使用灌胃法每日按照100mg／kg体重的剂量灌胃TNZ药液，连续5d。

TNZ in plasma and muscle tissues extracted with dichloromethane.

用二氯甲烷萃取血浆和肌肉中TNZ。

Conclusion TNZ can apparently control periodontitis symptoms and reduce the number of spirochete in oral bacteria.

结论局部应用替硝唑能明显抑制牙周炎症，降低螺旋体在口腔菌群中的比例，口腔螺旋体对替硝唑的敏感度有待进一步实验。