ZINACEF

CONCLUSIONS Cefuroxime sodium injection can effectively treat lower respiratory infection and urinary tract infection caused by sensitive pathogenic bacteria, and furthermore, the occurrence rate of side-effect is low, which similar to the import product Zinacef.

结论注射用头孢呋辛钠对临床常见的致病菌引起的下呼吸道感染、泌尿系感染，临床疗效较好且不良反应发生率低，与进口西力欣相近。

Objective: To evaluate and compare the efficacy and safety of domestic cefuroxime and Zinacef.

目的比较国产注射用头孢呋辛钠与进口注射用头孢呋辛钠（对照组）治疗下呼吸道感染的疗效和安全性。

The adverse reaction was evaluated in 86 cases of cefuroxime sodium group and 79 cases of Zinacef group. The adverse drug reaction rates were 10.5% ( 9/ 86) and 15.2% ( 12/ 79), respectively.

两组安全性评价分别为86例及79例，不良反应发生率分别为10.5%（9/86）与15.2%（12/79）。

Methods: 40 patients were recruited and divided into 2 group by random and mono blind methods, and treated with Cefuroxime sodium and Zinacef respectively.

方法：急性细菌感染性疾病患者40例，进行前瞻性多中心随机单盲平行对照试验，分别给予国产与进口头孢呋辛钠治疗。