In vitro antimicrobial activity of cefazolin combined with sulbactam against 90 clinical isolates producing beta-lactamase

Conclusion The cefazolin sodium pentahydrate had an excellent clinical efficacy and good safety profile in treating patients with bacterial infections.

结论五水头孢唑林钠治疗轻、中度急性下呼吸道细菌性感染，疗效确切，安全性较好。

Conclusion: A high tem-perature and humidity circumstance lead to the crystal modification of cefazolin sodium easily.

结论：在较高的温度、湿度环境中有利于头孢唑林钠α晶体向β晶体转变。

Methods: Powder X-ray diffraction was used to identify the crystal forms of cefazolin sodium in different temperature and humidity circum-stances;

方法：利用粉末X射线衍射（XRD）法分析了固体头孢唑林钠在不同的温度、湿度环境中α晶体、β晶体及无定型粉末之间的转变；

Analysis of Drug Use of Lincomycin Injection DDDs of cefazolin sodium, cefotaxime sodium and lincomycin injection took the lead.

林可霉素注射液用药分析注射用抗感染药物中头孢唑林钠、头孢噻肟钠和林可霉素针剂的用药频度均位列前3位。

Cefazolin sodium ( CEZ) is one of the first generation cephalosporins.

头孢唑林钠是第一代头孢类抗生素。

Determination of the Temperature Coefficient K of Optical Rotation of Cefazolin Sodium

头孢唑林钠旋光度温度系数K的测定

The resistant rates of imipenem, ceftazidime and cefoperazone/ sulbactam to ESBL strains were null percent. Except ampicillin, carbenicillin and cefazolin, other 9 β lactam antibiotics to ESBL negative strains were less than 6%.

亚胺培南、头孢他啶和头孢哌酮/舒巴坦的耐药率为0，除氨苄西林、羧苄西林和头孢唑林外，其他9种抗生素对非ESBL菌株的耐药率<6%。

The staphylococci ′ s durg fast rate to Ampicillin ( AM), Cefazolin, Oxacillin was about 70%.

葡萄球菌对氨苄青霉素、头孢唑林、苯唑青霉素的耐药率在70%左右。

In situ, in vivo, real time monitoring concentration of cefazolin sodium in rabbit plasma by microdialysis sampling and capillary electrophoresis with UV detection

毛细管电泳法检测微透析液中的头孢唑林钠

Application of the Kinetic Turbidimetric Limulus test for Cefazolin Sodium for injection

动态浊度法检测注射用头孢唑林钠中细菌内毒素

Preparations of cefotiam intermediate 7-ACMT and cefazolin intermediate TDA were discussed as raw material of 7-ACA.

以D-7-ACA为原料，探讨了头孢替安中间体7-ACMT和头孢唑林中间体TDA的合成。

Infection risk was related to choice of antibiotic prophylaxis, with the highest risk seen with the use of cefazolin.

感染风险与抗生素预防的选择之间是相关的，其中用头孢唑林预防者发生感染率最高。

Transdermal Iontophoresis Delivery of Cefazolin Sodium in Vitro and in Vivo

头孢唑林钠离子导入体内外透皮特性的研究

Objective To investigate and evaluate the characteristics of in vitro antibacterial activity of cefotaxime, cefoperazone, ceftriaxone, ceftazidime, cefuroxime and cefazolin for injection.

目的考察及评价注射用头孢噻肟钠、注射用头孢哌酮钠、注射用头孢曲松钠、注射用头孢他啶、注射用头孢呋辛钠和注射用头孢唑林钠6种头孢菌素的抗菌作用特点。

Antimicrobial activity of cefazolin ( CEZ) combined with a beta-lactamase inhibitor sulbactam ( SBT) against beta-lactamase producing strains of clinical isolates was studied in vitro using liquid dilution method compared with cefazolin alone.

用液体培养基试管二倍稀释法测定头孢唑林联合舒巴坦对常见临床分离产酶菌的最低抑菌浓度（MIC），并与头孢唑林进行比较。

The HPLC was used to measure the ongoing change of content of cefazolin sodium, cefoperazone sodium and piperacillin sodium after compatibility.

HPLC法测定配伍后头孢唑林钠、头孢哌酮钠、哌拉西林钠含量的经时变化。

Conclusion Synergistic antibacterial effects was observed in fosfomycin in combination with 14 antibacterials against MRS.

结论磷霉素与14种抗菌药物分别联用对MRS具有协同抗菌作用，尤其能够提高头孢唑林、阿米卡星、氧氟沙星对MRS的杀菌速度。

Process development of cefazolin sodium: solvation of the key intermediate, TDA

头孢唑林钠中间体TDA溶剂化物的工艺改进

Amikacin ( AMK) in the serum of healthy volunteers was determined by the improved microbiological method and was compared with combination of AMK and cefazolin ( CEZ).

采用微量微生物法对阿米卡星（AMK）单用及AMK与头孢唑林（CEZ）合用后，健康者体内AMK血药浓度进行测定；

Staphylococcus aureus and Escherichia coli resistant to nalidixic acid and norfloxacin were above 50%, while Salmonella paratyphi A was 96 97%, whose drug resistance to ampicillin and cefazolin had an obvious rise also ( P0.01);

金黄色葡萄球菌和大肠埃希菌对萘啶酸和诺氟沙星的耐药升至50%以上，甲型副伤寒沙门菌则高达96%～97%，对氨苄西林、头孢唑林也都有明显升高（P0.01）；