Objective To construct an attenuated Salmonella typhimurium vaccine strain expressing the gene EspA of EHEC O157: H7 with balanced lethal system.

Utilization of λ-Red Recombination System and Balanced Lethal System to Reconstruct the Plasmid with Antibiotic Resistant Gene Using in Live Vaccine

利用λ-Red重组系统和平衡致死系统改造抗药性致腹泻工程疫苗

This will be of benefit to constructing the balanced lethal system of Shigella.

这为以asd基因作为靶基因构建痢疾菌的载体宿主平衡致死系统创造了条件。

The acute toxicity of DI was studied in 6 Beagle dogs with approximate lethal dose method ( ALD). General status, ECG and parameters of hematology, blood biochemistry and urine were measured to evaluate the toxicity.

用近似致死剂量法（ALD）观察得力康注射液对6条Beagle犬的急性毒性，观察其一般情况、心电图、血液学、血液生化、尿液检查。

The Dq value of the cell survival curve was 2.152 for 973 and 0.626 for CNE-1 cell line detected by the colony assay, which indicates that the sublethal damage repair in 973 cells being much faster than in CNE-1 cells.

细胞存活曲线显示，973细胞的Dq值为2.152，CNE1细胞的Dq值为0.626，提示973细胞的亚致死损伤修复能力大于CNE1细胞。

Relationship of sublethal damage repair modify factor and half repair time and fraction interval

修正因子与半修复时间及照射间隔时间关系

Dose range of brain death and behavioral changes following supralethal dose γ-irradiation in rats

大鼠受γ线超致死剂量照射后脑型放射病的剂量范围和行为的改变

Protective effects of head shielding on incapacitation after supralethal γ-irradiation in rats

头部屏蔽对大鼠超致死剂量γ线照射后失能的防护作用

The experiment suggests that there are regular changes in microcirculation of intestinal villi after supralethal whole-body irradiation.

本实验证明，超致死剂量全身照射后小肠绒毛微循环有明显的规律性变化。

The abnormal shape of ceils is probably resulted from the pathologic and compensative reaction of the injuried intestinal stem cells which resume their vital activity within a short period after supralethal irradiation.

畸形细胞的出现可能是致伤而未致死的小肠上皮干细胞在短暂时间内继续其生命活动的一种病理性代偿反应。

The misshaped cells occured in small intestinal epithelia after supralethal irradiation

超致死量照射后出现的小肠上皮畸形细胞及其意义

On the mycotic infection in acute radiation sickness after supralethal irradiation

超致死量照射急性放射病的霉菌感染问题

The frequency of dominant lethal mutation induced by X-irradiation is 2.1995 × 10-3 gamete · 10mGy.

X射线在该期诱发的显性致死突变率是2.1995×10~（-3）/（配子·10mGy）。

Relationship between chromosomal aberration of germ cells and dominant lethal mutation in male mice after low dosage of X-irradiation

小剂量X射线诱发雄性小鼠生殖细胞染色体畸变与显性致死间关系

Dominant lethal mutation in mice induced by low dose tritiated water

低剂量氚水诱发雄性小鼠显性致死突变的研究

Theeffect of dominant lethal mutation is higher than that of the aneuploid.

显性致死突变的效应比非整倍体胚胎的效应高。

Conclusions: Radiotherapy is the first choice for lethal midline granuloma. The recommended dose is 50~ 60Gy for 5~ 6 weeks. Chemotherapy can improve the symptoms, but can not increase the survival rate.

结论：放疗是恶性肉芽肿首选治疗方法，肿瘤量以50～60Gy／5～6w为宜，化疗可改善症状但不提高远期生存率。

The results showed 100% positive reaction in the patients with nasopharyngeal carcinoma, lethal midline granuloma and tonsillar malignant lymphoma;

结果表明：鼻咽癌、恶性肉芽肿和扁桃体恶性淋巴瘤病人全部阳性，其他如喉癌、鼻腔鼻窦癌、甲状腺癌等病人中也有部分阳性结果。

Objective: To retrospectively analyze the effect of radiotherapy for 30 cases of lethal midline granuloma and prognostic factors.

目的：回顾性分析30例恶性肉芽肿放射治疗效果和与预后有关的因素。

Nasal NK/ T-cell lymphoma was named as malignant midline reticulosis, polymorphic reticulosis, lethal midline granuloma, malignant granuloma, necrosis granuloma, angiocentric T-cell lymphoma, T-cell lymphoma of midline, peripheral T-cell lymphoma of midline etc in the past.

旧称中线恶性网状细胞增生症、多形性网状细胞增生症、致死性中线肉芽肿、恶性肉芽肿、坏死性肉芽肿、血管中心性T细胞淋巴瘤、中线T细胞淋巴瘤及中线外周T细胞淋巴瘤等。

Research on MLD Modeling and Simulation of a Class of Integrated Control Systems

一类综合控制系统的MLD建模与仿真研究