Evaluation of an aldose reductase inhibitor on lens metabolism, ATPases and antioxidative defense in streptozotocin-diabetic rats: an intervention study

Methods Female Wistar rats were injected a low dose of streptozotocin ( 30mg/ kg) intraperitoneally followed by a high fat high fructose diet and drank 10% fructose water.

方法腹腔注射小剂量链脲霉素（streptozotocin，STZ），30mg/kg轻度损伤胰岛β细胞，造成大鼠糖耐量异常后加喂高果糖高脂肪饲料，并饮用10%果糖水，造成胰岛素抵抗。

Streptozocin induced hyperglycemia significantly inhibited amygdala kindling development ( p0.01).

链脲霉素引起的高血糖抑制大鼠杏仁核点燃发展进程（p0.01）。

Methods: The solution of BCP ( three different doses) had been poured into stomach of rats for 15 days. Then STZ ( 55mg/ kg) were injected into abdominal cavity of them.

方法：给大鼠灌胃3个不同剂量的牛初乳粉（BCP）溶液15d后腹腔注射链脲霉素（STZ）55mg/kg。

AG dramatically decreased the pyridoxal phosphate level of diabetic rat liver, whereas PL-AG only moderately affected it.

AG给药后引起链脲霉素糖尿病大鼠肝磷酸吡哆醛含量严重低下，但PL-AG仅仅轻度影响肝磷酸吡哆醛含量。

Expression of A β_ ( 1-40) and A β_ ( 1-42) after intracerebroventricular injection of streptozotocin in rats

侧脑室注射链脲霉素引起大鼠脑Aβ（1-40）和Aβ（1-42）表达增加

In the present investigation, effect of bitter gourd on streptozotocin-induced diabetic rats with particular emphasis on kidney heparan sulfate ( HS) was studied.

本研究重点观察苦瓜对链脲霉素诱导的糖尿病大鼠肾脏硫酸类肝素的调节作用。

Methods Rats were made diabetic with streptozotocin. group D, streptozotocin-induced diabetic rats;

方法建立链脲霉素诱导的大鼠糖尿病模型。D组：糖尿病组；

Methods: The diabetic mouse model was established by injecting Streptozotocin ( STZ) in abdominal cavity.

方法：采用腹腔注射链脲菌素（STZ）的方法建立小鼠糖尿病模型；

Dose-response Relationship of Diabetes Model Induced by Streptozocin in Neonatal Rats and Changes of Thymocyte Proliferation Activity

链脲菌素诱发新生期大鼠糖尿病的量效关系及其胸腺淋巴细胞增殖活性的变化

Methods: The latency of PERG-q and FERG-b in the normal and streptozotocin-induced diabetic rats within 8 weeks was recorded and statistically analysed.

方法：用图形视网膜电图（PERG）和闪光视网膜电图（FERG）分别记录正常和链脲菌素诱导的糖尿病大鼠8周以内PERG-q波及FERG-b波潜时，并进行统计学分析。

Rats from DM group and Tau group were given 50 mg/ kg streptozotocin ( STZ) by intraperitoneal injection.

DM组和Tau组腹腔注射链脲菌素（STZ）50mg/kg复制DM大鼠模型。

Insulin-dependent diabetic model were induced with an intraperitoneal injection of streptozotocin ( STZ), and rats in the normal control group were given of citrate buffer solution at the same volume.

给予大鼠一次性腹腔注射链脲菌素造成胰岛素依赖性糖尿病模型，正常对照组给予等体积的柠檬酸盐缓冲液。

Study on the Redox Regulation of Somatostatin in Diabetes Mice Induced by STZ

生长抑素对链脲菌素诱导糖尿病小鼠氧化还原调控作用的研究

Glucose and insulin levels in serum, androgen-binding protein ( ABP) and nuclear androgen receptor ( NAR) in testis were determined in streptozocin-induced diabetic and the control Wistar rats.

静脉注射链脲菌素复制糖尿病模型后80天，处死动物，测定血糖，血浆胰岛素浓度及睾丸雄激素结合蛋白（ABP）和细胞核雄激素受体。

AIM: To compare serum tumor necrosis factor α( TNF α) concentration in liver specific glucokinase gene knockout mice and two kinds of streptozotocin induced diabetic mice, and to explore the possible role of TNF α in the pathogenesis of diabetes mellitus.

目的：通过比较肝脏特异性葡萄糖激酶基因敲除小鼠和两种链脲菌素诱导的糖尿病小鼠模型血清肿瘤坏死因子α（TNFα）水平，初步探讨TNFα在糖尿病发病过程中的作用。

Suppression of insulitis and diabetes in Kunming mice by oral bovine protamine zinc insulin

口服牛胰岛素在昆明株小鼠抑制了链脲菌素引起的糖尿病及胰岛炎

Method: Streptozotocin DN model was built and influenced with the compound of traditional Chinese drugs and Benazepril.

方法：建立2型链脲菌素DN模型，以中药复方、苯那普利干预。

Experimental study on the relationship between chymase activity and cardiomyopathy in STZ-induced diabetic hamsters

糜蛋白酶活性与链脲菌素诱导糖尿病仓鼠心肌病变的研究Chymase在STZ糖尿病仓鼠心肌病变形成中的意义

Methods: DM rat models were established successfully by streptozocin ( STZ) injection which caused high level of blood glucose in Wistar rats.

方法：采用链脲菌素（STZ）诱发Wistar大鼠产生高血糖，建立1型糖尿病大鼠模型。

Methods: Glycemia, glycosylated hemoglobin, urinary microalbumin, kidney weight/ body weight and renal pathological changes were examined through glucose oxidase assay and ELISA in diabetic male rats induced by streptozotocin.

方法：以链脲菌素诱导大鼠糖尿病模型，采用葡萄糖氧化酶法、EUSA法、肾重/体重及组织学等方法检测糖尿病大鼠血糖、尿微量白蛋白、肾脏肥大及肾脏病理形态等变化。