Medicine intermediate N-ethylethylenediamine ( NEED ) was synthesized from acrylamide and ethylamine by addition reaction and Hofmann rearrangement.

  • 以丙烯酰胺为起始原料,经乙胺加成后,再经Hofmann重排两步反应后合成了药物中间体N - 乙基乙二胺 ( NEED ).

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