Azoles are the largest class of antifungal agents in clinical use. 1,2,3-Triazole moieties are attractive connecting units, as they are stable to metabolic degradation and capable of hydrogen bonding, which can be favorable in binding of biomolecular targets and solubility.

  • 唑类是临床上应用最广泛的抗菌药物。1,2,3-三氮唑由于其不容易被生物降解和容易形成氢键增加了其与生物大分子的结合能力,被作为一个极具吸引力的连接单元广泛应用。

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