The expression of MMP-9 was significantly increased in mesangial proliferative glomeruli and interstitial vascular walls of IgA nephropathy patients ( P < 0.001), but markedly decreased in sclerotic glomeruli and not apparently altered in the tubule. No expression of TIMP-1 could be detected in normal renal tissue.

  • 在IgA肾病中,MMP9在系膜增殖性肾小球和间质血管壁的表达均明显增多(P<0001),而在硬化肾小球内的表达则明显减少,肾小管细胞的MMP9表达无明显变化。

  • 互联网摘选 2025-01-20 11:36:16

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