COX-1 is the constitutive gene, whereas COX-2 is inducible gene. Cytokines, growth factors, oncogenes, and tumor promoters have been found to induce COX-2 up-expression in order to produce prostaglandins ( PGs) for various inflammatory stimulation.

  • COX-1为组成性基因,COX-2是诱导型基因,受细胞因子、生长因子、癌基因、及肿瘤促进剂的刺激,COX-2表达上调,使其产生对各种炎症做出反应的前列腺素类物质(PGs)。

  • 互联网摘选 2025-01-20 11:38:48

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