The results indicated that saturated FFAs induced apoptosis of granulosa cell by their acly CoA metabolites in a dose dependent manner, and led to the down regulation of Bcl 2 and the up regulation of Bax.
结果表明,饱和脂肪酸通过其代谢产物酰基辅酶A呈剂量依赖性的引起颗粒细胞凋亡,并导致Bcl2水平下降和Bax水平升高。
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