vhl

Retinal hemangioblastomas may be the initial manifestation of VHL syndrome and can cause vision loss.

视网膜成血管瘤可能为VHL综合征首先发现的类型,通常表现为失明.

Results Combining with the familial history, individual history, radiology and pathology, the diagnosis of VHL can be made.

结果结合家族史、个人史、影像学检查以及手术病理证实其诊断。

Objective To discuss imaging features of von Hippel-Lindau disease ( VHL disease).

目的探讨von Hippel-Lindau病（VHL病）的影像学特征。

The mutations of VHL gene were irrespective of the age and pathological grade and stage of patients.

结论：国人非遗传性肾透明细胞癌中存在VHL基因的突变，且与患者年龄，肿瘤分期、分级无相关性。

Somatic mutations of VHL gene and HIF-1 α expression in primary renal clear cell carcinomas

肾透明细胞癌中VHL基因突变与缺氧诱导因子-1α表达的研究

Expression of VHL and HIF-1 α and its clinical significance in the lung cancer tissue

肺癌组织中VHL和HIF-1α表达及其临床意义

Conclusion Imaging techniques still play an important role in the evaluation and management of VHL disease.

结论影像学检查在冯·希佩尔·林道病的诊治中仍起着极其重要的作用。

The detection of mutations in VHL gene from a single cell in a patient with von Hippel-Lindau disease

单细胞水平检测von Hippel-Lindau病基因突变的实验研究