ytt

Conclusion: The function of YTT and MFT in treating IRS may be related to those factors: enhancing ATPase activity decreasing ( Ca2+) I, inhibiting Ca2+ overload and resisting to lipids peroxidation of erythrocyte membrane.

结论：养心通脉片和二甲双胍对IRS患者的治疗作用可能与其提高ATP酶活性、降低（Ca2+）I含量、抑制Ca2+超载、对抗细胞膜脂质过氧化损伤，从而使细胞功能得到保护有关；

CONCLUSION: YTT is safe and effective in treatment of various osteoarthropathy, lumbar degeneration, lumbar muscle strain and sciatica.

结论：腰腿痛丸用于治疗各种骨关节炎、各种腰椎退行性变以及腰肌劳损、坐骨神经痛等疾病是安全和有效的。

OBJECTIVE : To evaluate the clinical efficacy and ADRs of Yaotuitong pills ( YTT ).

目的: 评价腰腿痛丸的临床疗效和不良反应.

OBJECTIVE: To evaluate the clinical efficacy and ADRs of Yaotuitong pills ( YTT).

目的：评价腰腿痛丸的临床疗效和不良反应。

Objective: To study the effects of Yangxing Tongmai Tablets ( YTT) on insulin receptor of Insulin Resistance Syndrome ( IRS).

目的：研究养心通脉片对胰岛素抵抗综合征（IRS）胰岛素受体的影响。

Conclusion: YTT had the roles with inhibiting over proliferation of vascular smooth muscle cells and preventing formation and development of IRS through improving insulin sensitivity, inhibiting C-myc mRNA expression and following reducing the level of PDGF-A mRNA.

结论：养心通脉片能通过改善机体胰岛素敏感性，抑制C-myc基因mRNA的表达，而下调PDGF-a mRNA的表达水平，有利于进一步抑制血管平滑肌细胞的过度增殖，防止IRS的发生、发展。