major issues;big problems;

Too much rain is the problem of the equatorial lands in the Amazon and Congo basins.
雨水过多是亚马逊河与刚果河流域赤道地区的大问题.
来源:《简明英汉词典》They are the great questions in the theory of capital which vexed economists in the past.
它们是在过去曾使经济学家伤脑筋的资本理论的大问题.
来源:辞典例句I'm afraid that these troubles are just a prelude , ie to worse ones.
我看这些为难事只是个引子(大问题在后面).
来源:词典精选例句
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