FMRP

Loss of fragile mental retardation protein ( FMRP) causes the fragile X mental retardation syndrome.

脆性X智力低下蛋白（fragile mental retardation protein，FMRP）的表达缺失引起一种遗传性智力低下疾病&脆性X综合征。

Objective To investigate neural pruning or neural plasticity of mouse somatosensory cortical barrel in the absence of fragile X mental retardation protein ( FMRP).

目的研究脆性X智力低下蛋白（FMRP）缺失对感觉皮质功能柱神经可塑性的影响。

Proteins interacting with FMRP were screened by yeast two-hybrid system.

应用酵母双杂交体系对FMRP的相互作用区域进行定位。

Now they are beginning to understand how FMRP regulates signaling pathways in the brain that are essential for learning and memory in adults.

现在他们开始知道脆性X智力低下蛋白在成人中是怎么调节对于学习和记忆非常重要的大脑信号通路的。

Objective To investigate the physiological role of fragile X mental retardation protein ( FMRP) and screen the proteins interacting with FMRP in human fetal hippocampus cDNA library.

目的筛选与脆性X智力低下蛋白（FMRP）相互作用的蛋白，为FMRP生理功能的阐释提供新线索。

Evaluation of peripheral blood lymphocyte FMRP detection for diagnosing fragile X syndrome in children

FMRP检测在儿童脆性X综合征中诊断价值的实验评价

Conclusion FMRP may participate in the development process of dendritic spine pruning in somatosensory barrel cortex and the mechanisms of pruning between dendrite and dendritic spine are different.

结论FMRP缺失导致树突棘密度增高和感觉皮质功能柱区域树突棘修剪异常，并且树突棘修剪和树突修剪的机制不同。