Analysis and expression in CHO/ dhfr~+ of recombinant human protein C

Construction of targeted integration and high expression system in CHO/ dhfr-cell line

新型CHO/dhfr~-细胞定点整合和表达系统的建立

Conclusions Patients with DHIC have more strength in voiding than those with simple impaired detrusor contractility.

结论DHIC的膀胱排空能力高于单纯逼尿肌收缩力减弱者。

Eleven patients suffered from upper urinary tract dilation; among them 8 patients had DHIC.

有上尿路扩张者11例，其中DHIC者8例。

It can be converted into dihydrolipoic acid ( DHLA) in mammal cells.

α-硫辛酸在哺乳动物细胞内可以部分转化为还原型的二氢硫辛酸（dihydrolipoic acid，DHLA）。

The present investigation can provide new free radical biological data for the further study on the medical and health-care applications of LA and DHLA.

本研究为LA和DHLA保健和药用价值的进一步开发，提供了自由基生物学方面的依据。

It seems that the antioxidation ability of DHLA is stronger than that of LA.

以上结果提示，DHLA的抗氧化能力明显强于LA。

METHODS N Dodecyl α hydroxyl propanamide ( DHPA) and N methyl dodecyl pyroglutamate ( MDPG) were synthesized.

方法合成了N月桂基α羟基丙酰胺（DHPA）和N甲基焦谷氨酸月桂酯（MDPG）。

Conclusion The combined treatment of ( S) DHPA and/ or ( RS) DHPA and HBO has inhibitory effect on Japanese encephalitis virus infection in experimental mice.

结果：（S）DHPA或/及（RS）DHPA与高压氧联合治疗可抑制人工感染小鼠体内日本乙型脑炎病毒的致病作用。

Methods The method of Dendrogram hierarchy process analytic ( DHPA), the Coryneform bacteria were identified with DHPA method and API CORYNE strip.

方法以HPA法为原理建立DHPA法，用DHPA法及API试条鉴定棒形菌。

The correct identification rate of DHPA method and API method were 84.5% and 78.9% respectively for 71 strains of Coryneform bacteria isolated from clinical specimens.

DHPA法与API法对71株临床菌株鉴定结果的准确性为84.5%和78.9%。

[ Results] The correct identification rate of DHPA method and ATB method was 83.4% for 331 strains of Micrococcaceae isolated from clinical specimens.

[结果]DHPA法和ATB法对微球菌科35个KIU鉴定的正确性分别为100%与94.3%；对331株临床分离微球菌的鉴定符合率为83.4%。

The total consistent identification rate of DHPA method and API method was 72% for 2082 test codes of Coryneform bacteria.

DHPA法与API法对棒形菌2028个试验编码分析的总符合率为100%。

Identification of coryneform bacteria by DHPA method and API coryne strip

DHPA法及API CORYNE试条鉴定棒形菌

Methods One hundred patients with unknown motor disturbance and mental retardation were referred to this study. All patients were performed by phenylalanine ( Phe) and BH4 loading test, urinary pterin analysis and dihydropteridine reductase ( DHPR) activity.

方法对100例运动及智能障碍患者进行苯丙氨酸（phenylalanine，Phe）及BH4负荷试验、尿蝶呤谱分析、红细胞二氢蝶啶还原酶测定，并对部分患者进行多巴治疗性诊断；

Urinary biopterin percentage and DHPR activity were all normal in 41 patients, so they were ruled out BH_ 4 deficiency.

41例尿蝶呤及DHPR活性均正常。

Conclusions The DHPR activity determination in red cell from dried blood spot is an effective, reliable and feasible method for diagnosis of DHPR deficiency.

结论干滤纸血片中红细胞DHPR活性测定是DHPR缺乏症有效、可靠且易行的诊断方法。

These results suggest that the3 fractions of DHPR may be structurally related but catalytically distinguishable.

这些结果告诉我们，不同组分的DHPR在结构上有某种联系但催化效应却有差别。

The Way of the Dynamic State Data Handled Synthetic Method ( DHSM) for Environmental Forecast

环境预测动态数据处理合成法

In order to improve effect of traditional modulation code, a new modulation-array ( MA) code and a novel soft-decision method corresponding to MA code are proposed for data processing in DHSS.

为了克服传统调制码的弊端，提出了一种适用于DHSS新的调制码：调制-阵列码的编译码方法及其相应的软判决度量方法。

Results: Among the patients with DHSS, 62.96% were Hp associated chronic gastritis ( compared with that in the group of SAS, P < 0.05).

结果：Hp相关性慢性胃炎中脾胃湿热型占62.96%（P<0.05）；