Twelve 20-hydroxyl ester analogues of camptothecin were prepared and evaluated in vitro antitumor activity.

  • 为了改善取代喜树碱的溶解性、抗肿瘤活性和毒副作用,设计合成了十二个新的取代喜树碱20-位羟基酯衍生物.

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