Three active compounds were isolated from the marine bryozoan Bugula neritina living in the South China Sea by bioassay-guiding isolation method with a combination of extraction with suitable solvent and multiple column chromatography ( Sephadex LH-20, ODS and preparative HPLC).

  • 以中国南海海域大量生长的总合草苔虫为原料,将化学分离和活性追踪相结合,经溶媒提取和多种层析方法(Sephadex LH-20,ODS,HPLC等)分离,得到3个活性单体。

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