Once out of the farm the approach of poverty would be sure.

However, these were nothing compared to what was about to happen.

然而这一切跟接踵而至的攻击事件比起来,根本就不算什么.

The great king felt himself at the end of his rope.

这位伟大的国王已感日暮途穷.

Are museums losing their grip?

博物馆大势已去?

He lost his position through circumstances beyond his control.

他大势已去,失去了职位(他因他所无法控制的情势而失去了自己的职位).

Seeing Xiang Yu lost, Ziwen generous in the Wujiang River Edge.

项羽眼见大势已去, 慷慨自刎于乌江边.

Charles was more realistic and knew that for the moment all was lost.

查理想得比较实际,他清楚眼下大势已去.

Then the die was cast.

这么一来,就大势已去了.

The sailor who had lost everything by shipwreck said that he was thrown on his beam-ends.

在海难事件中丧失一切的海员说,他已经面临穷途末路了.

Now you have come to the last extremity and have no one to rely on.

你现在穷途末路,举目无亲.

His cause is by no means hopeless.

他的事业并非穷途末路.

They are in a dire extremity.

他们在悲惨的穷途末路.

Poor old Tom, he's on his last pins.

可怜的老汤姆, 他已到了穷途末路.

The era of bold innovation is drawing to a close.

勇于创新的时代将是穷途末路.

This does not mean that ambition is at an end.

这并不意味着雄心已到了穷途末路.

In their extremity the people on the sinking ship bore themselves bravely.

在穷途末路,在逐渐下沈船上的人们表现的勇敢.

I wouldn't be here if I wasn't up to my hind end in inventory.

要不是我已经穷途末路了,我也不会在这了.

He is on his beam-ends.

他穷途末路了.

Now, it is making a come back.

现在它却死灰复燃了.

He died greatly in debt.

他死灰复燃时负债累累.

The last thing that they suspected was the return of smallpox.

他们最意想不到的,便是天花又死灰复燃.