PI3K/ Akt signaling pathway was activated in Pten-deficient articular chondrocytes. The Pten knockout mice gradually exhibit humpback, faltering steps and anchylosis as they grew up.

  • Pten敲除小鼠的关节软骨细胞中PI3K/Akt信号通路持续激活,成年的Pten敲除小鼠逐步表现出驼背、步履蹒跚、关节僵硬等OA大体表现。

  • 互联网摘选 2025-01-19 23:51:41

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